Comparative Evaluation of Anti-Inflammatory activity of different Extracts of Boswellia serrata in Wistar Albino Rats

نویسندگان

  • Joshua Allan
  • Krishna Goudar
  • A. Amit
چکیده

Inflammation is the local response of living mammalian tissues to injury due to any agent. It is the body defence reaction in order to eliminate or limit the spread of injurious agent, followed by removel of the necrosed cells and tissues, but the sign and symptoms which are produced during healing process can’t tolerable. The present study was aimed to investigate the anti-inflammatory activity of Commercial and Hexane extracts of Boswellia Serrata in wistar albino rats. In this study both acute and sub-acute inflammation models were used to evaluate the anti-inflammatory activity of Boswellia Serrata. In acute model Carrageenan was used to induce inflammation in rat hind paw and in subacute inflammation Cotton pellets induced granuloma was performed. The extracts has significantly (p ≤ 0.05) decrease in paw edema volume and wet weight and dry weight of Cotton pellets as compared to the untreated vehicle control group.

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تاریخ انتشار 2003